Quantitative metabolomics services for biomarker discovery and validation.
Specializing in ready to use metabolomics kits.
Your source for quantitative metabolomics technologies and bioinformatics.
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Unknown Unknown Unknown Cytochrome P450 1A2 Cytochrome P450 1A2 Cytochrome P450 3A4 Cytochrome P450 3A4 Tofacitinib Tofacitinib Tofacitinib PIS2M2 Tofacitinib PIS2M2 Tofacitinib PIS2M1 Tofacitinib PIS2M1 Tofacitinib PIS1M1 Tofacitinib PIS1M2 Heme Heme Heme Heme Urinary Excretion and/or Bile duct Excretion Endoplasmic Reticulum Cytosol Hepatocyte Blood Vessel Liver kidney Bile Duct Blood Vessel Tofacitinib undergoes metabolism to give Tofacitinib PIS1M1, Tofacitinib PIS1M2, Tofacitinib PIS1M3 and Tofacitinib PIS2M1. Endoplasmic Reticulum
Endoplasmic Reticulum Endoplasmic Reticulum Unknown Unknown Unknown CYP1A2 CYP1A2 CYP3A4 CYP3A4 Tofacitinib Tofacitinib Tofacitinib PIS2M2 Tofacitinib PIS2M2 Tofacitinib PIS2M1 Tofacitinib PIS2M1 Tofacitinib PIS1M1 Tofacitinib PIS1M2 Urinary Excretion and/or Bile duct Excretion