PathWhiz

PathWhiz ID	Pathway	Meta Data
PW122243 View Pathway	disease Aspartylglucosaminuria Homo sapiens Aspartylglucosaminuria (AGU) is an inherited disease that is characterized by a decline in mental functioning, accompanied by an increase in skin, bone and joint issues. The disease is caused by a defect in an enzyme known as aspartylglucosaminidase (normally present in the liver and brain as well as other tissues). This enzyme plays a significant role in our bodies because it aids in breaking down certain sugars (for example, oligosaccharides) that are attached to specific proteins (for example, glycoproteins). Aspartylglucosaminuria itself is characterized as a lysosomal disease because it does deal with inadequate activity in an enzyme's function. Aspartylglucosaminidase functions to break down glycoproteins. These proteins are most abundant in the tissues of the body and in the surfaces of major organs, such as the liver, spleen, thyroid and nerves. When glycoproteins are not broken down, aspartylglucosaminidase backs up in the lysosomes along with other substances. This backup causes progressive damage to the tissues and organs. Aspartylglucosaminuria is a genetic condition that is inherited from both parents. The AGU patient is born with two copies of the mutated AGA gene. One copy comes from the mother’s egg and the other copy comes from the father’s sperm. In order to develop aspartylglucosaminuria, the individual must inherit changes in both of his AGU genes (autonomic recessive inheritance). When a person receives one changed form of the gene AGU from one of the parents, the individual is then classified as a carrier [Wikipedia]. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: xuan cao Created On: October 01, 2018 at 11:15 Last Updated: October 01, 2018 at 11:15
PW124252 View Pathway	metabolic biosynthesis novo Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: October 19, 2020 at 17:50 Last Updated: October 19, 2020 at 17:50
PW124344 View Pathway	metabolic biosynthesis novo 1605518331 Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: November 16, 2020 at 02:19 Last Updated: November 16, 2020 at 02:19
PW123844 View Pathway	metabolic chebulagic acid Metabolism Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: March 26, 2020 at 04:33 Last Updated: March 26, 2020 at 04:33
PW122545 View Pathway	signaling chebulagic acid Metabolism 1550463482 1563965617 Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: July 24, 2019 at 04:54 Last Updated: July 24, 2019 at 04:54
PW124069 View Pathway	signaling chebulagic acid Metabolism 1559277983 1589861306 1597248631 Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: August 12, 2020 at 10:10 Last Updated: August 12, 2020 at 10:10
PW124042 View Pathway	signaling chebulagic acid Metabolism 1559277983 1596798296 Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: August 07, 2020 at 05:05 Last Updated: August 07, 2020 at 05:05
PW123794 View Pathway	signaling chebulagic acid Metabolism 1581167212 Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: February 08, 2020 at 06:07 Last Updated: February 08, 2020 at 06:07
PW123807 View Pathway	signaling chebulagic acid Metabolism 1581839290 Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: February 16, 2020 at 00:48 Last Updated: February 16, 2020 at 00:48
PW064753 View Pathway	metabolic Mapa metabólico Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: June 10, 2018 at 16:58 Last Updated: June 10, 2018 at 16:58