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Beta-Ala-His dipeptidase Carnosine synthase 1 Protein arginine N- methyltransferase 3 Histidine decarboxylase Histamine N- methyltransferase Amine oxidase [flavin- containing] A Aldehyde dehydrogenase, dimeric NADP-preferring Aldehyde dehydrogenase, mitochondrial Histidine ammonia-lyase Urocanate hydratase Probable imidazolonepropionase Formimidoyltransferase- cyclodeaminase Amiloride- sensitive amine oxidase [copper- containing] Carnosine N- methyltransferase Carnosine synthase 1 cytosolic non-specific dipeptidase Probable histidine--tRNA ligase, mitochondrial Histidine--tRNA ligase, cytoplasmic L-Glutamic acid Carnosine H2O β-Alanine L-Histidine ATP β-Alanine ADP Pi S- Adenosylmethionine 3-Methylhistidine S- Adenosylhomocysteine Histamine CO2 S- Adenosylmethionine S- Adenosylhomocysteine 1-Methylhistamine H2O O2 Methylimidazole acetaldehyde NH3 H2O2 NADP H2O Methylimidazoleacetic acid NADPH H+ Imidazole-4- acetaldehyde NAD H2O Imidazoleacetic acid NADH H+ NH3 Urocanic acid 4-Imidazolone- 5-propionic acid H2O H2O Formiminoglutamic acid Tetrahydrofolic acid 5- Formiminotetrahydrofolic acid H2O O2 NH3 H2O2 S- Adenosylmethionine S- Adenosylhomocysteine Anserine ATP 1-Methylhistidine β-Alanine ADP Pi H2O β-Alanine ATP AMP PPi ATP AMP PPi Pyridoxal 5'-phosphate tRNA(His) L- Histidyl- tRNA(His) tRNA(His) Glutamate Metabolism Zinc (II) ion Manganese FAD NAD Zinc (II) ion Pyridoxal 5'-phosphate Copper Calcium Topaquinone Manganese Manganese Intracellular Space Extracellular Space Mitochondria Mitochondria