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Pathway Description
Abciximab Action Pathway (old)
Homo sapiens
Drug Action Pathway
Abciximab (also known as c7E3 Fab) is integrin (integrin alpha-IIb and integrin beta-3) receptor antagonist. Binding of abciximab to integrin receptor will block any large molecule to attach on the receptor, which will lead to block any associated signal transduction pathways.
References
Abciximab Pathway (old) References
Ciccone A, Abraha I, Santilli I: Glycoprotein IIb-IIIa inhibitors for acute ischaemic stroke. Cochrane Database Syst Rev. 2006 Oct 18;(4):CD005208. doi: 10.1002/14651858.CD005208.pub2.
Pubmed: 17054247
Jennings LK, Saucedo JF: Antiplatelet and anticoagulant agents: key differences in mechanisms of action, clinical application, and therapeutic benefit in patients with non-ST-segment-elevation acute coronary syndromes. Curr Opin Cardiol. 2008 Jul;23(4):302-8. doi: 10.1097/HCO.0b013e3283021ad9.
Pubmed: 18520712
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