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CREB3L2-PPARgamma
Acetylglutamate
kinase
Acetylornithine/succinyldiaminopimelate
aminotransferase
Carbamoyl-
phosphate
synthase large
chain
Carbamoyl-
phosphate
synthase small
chain
Argininosuccinate
synthase
Argininosuccinate
lyase
Arginine N-
succinyltransferase
N-
succinylarginine
dihydrolase
Succinylornithine
transaminase
N-
succinylglutamate
5-semialdehyde
dehydrogenase
Succinylglutamate
desuccinylase
Gamma-
glutamylputrescine
synthetase
Gamma-
glutamylputrescine
oxidoreductase
Gamma-glutamyl-
gamma-
aminobutyraldehyde
dehydrogenase
Putrescine
aminotransferase
Gamma-
aminobutyraldehyde
dehydrogenase
4-aminobutyrate
aminotransferase_
4-aminobutyrate
aminotransferase
Aldehyde
dehydrogenase-
like protein yneI
Acetylornithine
deacetylase
Biodegradative
arginine
decarboxylase
N-acetyl-gamma-
glutamyl-
phosphate
reductase
Ornithine
carbamoyltransferase
chain F
Ornithine
carbamoyltransferase
chain I
Agmatinase
Gamma-glutamyl-
gamma-
aminobutyrate
hydrolase
Succinate-
semialdehyde
dehydrogenase
[NADP+]
Succinic acid
Succinic acid
L-Glutamic acid
Acetyl-CoA
CoA
H
+
N-Acetyl-L-
glutamic acid
ATP
ADP
N-Acetyl-L-
glutamyl
5-phosphate
N-Acetyl-L-
glutamate
5-semialdehyde
L-Glutamic acid
Oxoglutaric acid
N-Acetylornithine
HCO
3
-
H
2
O
L-Glutamine
ATP
ADP
P
i
L-Glutamic acid
H
+
Carbamoyl
phosphate
ATP
Citrulline
L-Aspartic acid
PP
i
AMP
Argininosuccinic
acid
Fumaric acid
L-Arginine
Succinyl-CoA
CoA
H
+
N2-succinyl-L-
arginine
H
2
O
H
+
CO
2
Ammonium
N2-Succinyl-L-
ornithine
Oxoglutaric acid
L-Glutamic acid
N2-Succinyl-L-
glutamic acid
5-semialdehyde
H
2
O
NAD
H
+
NADH
N2-
succinylglutamate
H
2
O
L-Glutamic acid
Putrescine
ATP
L-Glutamic acid
P
i
ADP
H
+
γ-glutamyl-L-
putrescine
O
2
H
2
O
4-(γ-
glutamylamino)butanal
Ammonium
H
2
O
2
H
2
O
NADP
4-(Glutamylamino)
butanoate
H
+
NADPH
Oxoglutaric acid
L-Glutamic acid
4-
Aminobutyraldehyde
H
2
O
NAD
H
+
NADH
γ-Aminobutyric
acid
Oxoglutaric acid
Succinic acid
semialdehyde
L-Glutamic acid
NAD
H
2
O
H
+
NADH
H
2
O
Ornithine
Acetic acid
H
+
Agmatine
CO
2
NADPH
H
+
NADP
P
i
P
i
H
+
H
2
O
Urea
H
2
O
L-Glutamic acid
H
2
O
NADP
NADPH
H
+
TCA Cycle
TCA Cycle
Plasmid
Cytoplasm
Inner Membrane
Periplasm
Gram-Negative Cell
Outer Membrane