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L-aspartate
oxidase
Quinolinate
synthase A
Nicotinate-
nucleotide
pyrophosphorylase
[carboxylating]
Nicotinate-
nucleotide
adenylyltransferase
NH(3)-dependent
NAD(+)
synthetase
NH(3)-dependent
NAD(+)
synthetase
L-Aspartic acid
O
2
H
2
O
2
H
+
Iminoaspartic
acid
Dihydroxyacetone
phosphate
P
i
H
2
O
Quinolinic acid
H
+
Phosphoribosyl
pyrophosphate
CO
2
PP
i
nicotinate β-D-
ribonucleotide
ATP
H
+
PP
i
Nicotinic acid
adenine
dinucleotide
ATP
Ammonium
H
+
AMP
PP
i
NAD
H
2
O
L-Glutamine
ATP
H
+
AMP
PP
i
L-Glutamic acid
Aspartate
Metabolism
nadB
nadA
nadC
nadD
nadE
nadE
L-Aspartic acid
Oxygen
Hydrogen
peroxide
Hydrogen Ion
Iminoaspartic
acid
Dihydroxyacetone
phosphate
Phosphate
Water
Quinolinic acid
Hydrogen Ion
Phosphoribosyl
pyrophosphate
Carbon dioxide
Pyrophosphate
nicotinate β-D-
ribonucleotide
Adenosine
triphosphate
Hydrogen Ion
Pyrophosphate
Nicotinic acid
adenine
dinucleotide
Adenosine
triphosphate
Ammonium
Hydrogen Ion
Adenosine
monophosphate
Pyrophosphate
NAD
Water
L-Glutamine
Adenosine
triphosphate
Hydrogen Ion
Adenosine
monophosphate
Pyrophosphate
L-Glutamic acid
Aspartate
Metabolism
nadB
nadA
nadC
nadD