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Carbamoyl- phosphate synthase large chain Carbamoyl- phosphate synthase small chain Aspartate carbamoyltransferase catalytic chain Aspartate carbamoyltransferase regulatory chain Dihydroorotase Orotidine 5'-phosphate decarboxylase Uridylate kinase Nucleoside diphosphate kinase CTP synthase Ribonucleoside- diphosphate reductase 1 subunit beta Ribonucleoside- diphosphate reductase 1 subunit alpha Anaerobic ribonucleoside- triphosphate reductase Ribonucleoside- diphosphate reductase 1 subunit beta Nucleoside diphosphate kinase Anaerobic ribonucleoside- triphosphate reductase Deoxycytidine triphosphate deaminase Dihydroorotate dehydrogenase Thymidylate synthase Orotate phosphoribosyltransferase Ribonucleoside- diphosphate reductase 2 subunit alpha Ribonucleoside- diphosphate reductase 2 subunit beta Nucleoside diphosphate kinase Ribonucleoside- diphosphate reductase large chain 1 Ribonucleoside- diphosphate reductase small chain 2 Deoxyuridine 5'-triphosphate nucleotidohydrolase Protein mazG Nucleoside triphosphatase nudI Nucleoside diphosphate kinase Anaerobic ribonucleoside- triphosphate reductase Phosphoribosyl pyrophosphate L-Glutamine HCO3- H2O ATP ADP Pi L-Glutamic acid H+ Carbamoyl phosphate L-Aspartic acid Pi H+ N-carbamoyl- L-aspartate H+ H2O 4,5- Dihydroorotic acid Orotidylic acid H+ CO2 Uridine 5'- monophosphate ATP ADP Uridine 5'-diphosphate ATP Uridine triphosphate ADP L-Glutamine H2O ATP ADP H+ Pi L-Glutamic acid Cytidine triphosphate H2O Pi H+ CDP H2O dCDP H2O dUDP ATP dTDP ADP Thymidine 5'-triphosphate H2O dCTP H2O H+ Ammonium Deoxyuridine triphosphate Ubiquinone-1 Ubiquinol-1 Orotic acid dUMP 5,10- methenyltetrahydrofolate mono-L- glutamate Dihydrofolic acid 5-Thymidylic acid PPi H2O ATP ADP H2O H2O Pi H+ ATP ADP H2O Adenosine triphosphate Zinc Guanosine triphosphate Magnesium Magnesium Adenosine triphosphate Fe2+ Magnesium Magnesium Adenosine triphosphate dGTP Thymidine 5'-triphosphate Potassium Magnesium Zinc (II) ion 4Fe-4S Flavin Mononucleotide Magnesium Magnesium Zinc Magnesium Magnesium Adenosine triphosphate dGTP Thymidine 5'-triphosphate Potassium Magnesium Zinc (II) ion 4Fe-4S reduced thioredoxin oxidized thioredoxin reduced thioredoxin oxidized thioredoxin a reduced flavodoxin an oxidized flavodoxin a reduced NrdH glutaredoxin- like protein an oxidized NrdH glutaredoxin- like protein a reduced NrdH glutaredoxin- like protein an oxidized NrdH glutaredoxin- like protein a reduced flavodoxin an oxidized flavodoxin PRPP Biosynthesis L-glutamate metabolism II