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dGTP Amidophosphoribosyltransferase Phosphoribosylamine- -glycine ligase Phosphoribosylglycinamide formyltransferase 2 Phosphoribosylformylglycinamidine synthase Phosphoribosylformylglycinamidine cyclo-ligase Phosphoribosylaminoimidazole carboxylase ATPase subunit Phosphoribosylaminoimidazole carboxylase catalytic subunit Phosphoribosylaminoimidazole- succinocarboxamide synthase Adenylosuccinate lyase Bifunctional purine biosynthesis protein purH Bifunctional purine biosynthesis protein purH Inosine-5'- monophosphate dehydrogenase Adenylosuccinate synthetase Adenylosuccinate lyase Adenylate kinase GMP synthase [glutamine- hydrolyzing] Guanylate kinase Nucleoside diphosphate kinase Anaerobic ribonucleoside- triphosphate reductase Ribonucleoside- diphosphate reductase 1 subunit beta Nucleoside diphosphate kinase Ribonucleoside- diphosphate reductase 2 subunit beta ATP synthase subunit c ATP synthase subunit b ATP synthase subunit a ATP synthase epsilon chain ATP synthase subunit delta ATP synthase subunit alpha ATP synthase gamma chain ATP synthase subunit beta Anaerobic ribonucleoside- triphosphate reductase Anaerobic ribonucleoside- triphosphate reductase Ribonucleoside- diphosphate reductase 1 subunit beta Ribonucleoside- diphosphate reductase 2 subunit alpha Ribonucleoside- diphosphate reductase 2 subunit beta Nucleoside diphosphate kinase Phosphoribosyl pyrophosphate H 2 O L-Glutamine 5- Phosphoribosylamine L-Glutamic acid PP i Glycine ATP N1-(5- phospho-β-D- ribosyl)glycinamide P i ADP H + ATP Formic acid 5'- Phosphoribosyl- N- formylglycinamide ADP P i H + H 2 O L-Glutamine ATP 2- (Formamido)- N1-(5- phospho-D- ribosyl)acetamidine L-Glutamic acid P i ADP H + ATP 5- Aminoimidazole ribonucleotide P i ADP H + HCO 3 - ATP N5- Carboxyaminoimidazole ribonucleotide ADP P i H + 5-amino-1-(5- phospho-D- ribosyl)imidazole- 4-carboxylate L-Aspartic acid ATP SAICAR P i ADP H + AICAR Fumaric acid FAICAR Inosinic acid H 2 O NAD H 2 O NADH H + Xanthylic acid L-Aspartic acid GTP GDP P i H + N(6)-(1,2- dicarboxyethyl)AMP Fumaric acid Adenosine monophosphate ATP Adenosine diphosphate ATP L-Glutamine H 2 O AMP PP i L-Glutamic acid H + Guanosine monophosphate ATP ADP Guanosine diphosphate ATP ADP Guanosine triphosphate H 2 O H 2 O dGDP ATP ADP dGTP H 2 O dGDP P i H + H 2 O H + Adenosine triphosphate H 2 O dATP Adenosine diphosphate H 2 O dADP H 2 O dADP ATP ADP dATP Magnesium Magnesium Potassium Magnesium Magnesium Magnesium Magnesium Magnesium Adenosine triphosphate dGTP Thymidine 5'-triphosphate Potassium Magnesium Zinc (II) ion 4Fe-4S Magnesium Adenosine triphosphate dGTP Thymidine 5'-triphosphate Potassium Magnesium 4Fe-4S Magnesium an N10-formyl- tetrahydrofolate a tetrahydrofolate a reduced flavodoxin an oxidized flavodoxin reduced thioredoxin oxidized thioredoxin a reduced NrdH glutaredoxin- like protein an oxidized NrdH glutaredoxin- like protein a reduced flavodoxin an oxidized flavodoxin reduced thioredoxin oxidized thioredoxin a reduced NrdH glutaredoxin- like protein an oxidized NrdH glutaredoxin- like protein PRPP Biosynthesis Folate Biosynthesis Anaerobic ribonucleoside- triphosphate reductase Ribonucleoside- diphosphate reductase 2 subunit alpha Zinc (II) ion