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Phosphoribosylglycinamide formyltransferase 2 Bifunctional protein folD Bifunctional polymyxin resistance protein ArnA Formyltetrahydrofolate deformylase Phosphoribosylglycinamide formyltransferase 2 Bifunctional purine biosynthesis protein purH Methionyl-tRNA formyltransferase Methionine synthase 5,10- methylenetetrahydrofolate reductase Thymidylate synthase Serine hydroxymethyltransferase Dihydrofolate reductase Dihydrofolate reductase Dihydrofolate reductase Aminomethyltransferase Aminomethyltransferase Bifunctional protein folD Dihydrofolic acid 5'- phosphoribosyl- a-N- formylglycineamidine Tetrahydrofolic acid H2O Glycineamideribotide 5,10- Methenyltetrahydrofolic acid NADPH NADP 4-Amino-4- deoxy-L- arabinose Tetrahydrofolate UDP-4-Deoxy- 4-formamido- β-L-arabinose Formic acid H2O 5'- Phosphoribosyl- N- formylglycinamide Glycineamideribotide FAICAR 1-(5'- Phosphoribosyl)- 5-amino-4- imidazolecarboxamide 5- Methyltetrahydrofolic acid Homocysteine L-Methionine 5,10- Methylene-THF NADPH H+ NADP 5-Thymidylic acid dUMP L-Serine Glycine H2O Folic acid NADPH H+ NADP NADP NADPH H+ NADPH H+ NADP NH3 H2O N5-Formyl-THF H+ H2O S- Aminomethyldihydrolipoylprotein; dihydrolipoylprotein N- formylmethionyl- tRNA(fMet) L-Methionyl- tRNA(Met) Folate Biosynthesis 10- Formyltetrahydrofolate
purT folD arnA purU purT purH fmt metH metF thyA glyA folA folA folA gcvT gcvT folD Dihydrofolic acid 5'- phosphoribosyl- a-N- formylglycineamidine Tetrahydrofolic acid Water Glycineamideribotide 5,10- Methenyltetrahydrofolic acid NADPH NADP 4-Amino-4- deoxy-L- arabinose Tetrahydrofolate UDP-4-Deoxy- 4-formamido- β-L-arabinose Formic acid Water 5'- Phosphoribosyl- N- formylglycinamide Glycineamideribotide FAICAR 1-(5'- Phosphoribosyl)- 5-amino-4- imidazolecarboxamide 5- Methyltetrahydrofolic acid Homocysteine L-Methionine 5,10- Methylene-THF NADPH Hydrogen Ion NADP 5-Thymidylic acid dUMP L-Serine Glycine Water Folic acid NADPH Hydrogen Ion NADP NADP NADPH Hydrogen Ion NADPH Hydrogen Ion NADP Ammonia Water N5-Formyl-THF Hydrogen Ion Water S- Aminomethyldihydrolipoylprotein; dihydrolipoylprotein N- formylmethionyl- tRNA(fMet) L- Methionyl- tRNA(Met) Folate Biosynthesis