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Isochorismate
synthase entC
2-succinyl-5-
enolpyruvyl-
6-hydroxy-3-
cyclohexene-
1-carboxylate
synthase
2-succinyl-6-
hydroxy-2,4-
cyclohexadiene-
1-carboxylate
synthase
o-
succinylbenzoate
synthase
2-
succinylbenzoate-
-CoA ligase
Naphthoate
synthase
1,4-
dihydroxy-2-
naphthoyl-CoA
thioesterase
1,4-
dihydroxy-2-
naphthoate
octaprenyltransferase
Ubiquinone/menaquinone
biosynthesis
methyltransferase
ubiE
1,4-
dihydroxy-2-
naphthoate
octaprenyltransferase
Hydrogenase-1
small chain
Hydrogenase-1
large chain
Probable Ni/Fe-
hydrogenase 1
B-type
cytochrome
subunit
Chorismate
isochorismate
Oxoglutaric
acid
H
+
CO
2
2-succinyl-5-
enolpyruvyl-
6-hydroxy-3-
cyclohexene-
1-carboxylate
(1R,6R)-6-
hydroxy-2-
succinylcyclohexa-
2,4-diene-1-
carboxylate
Pyruvic acid
2-
succinylbenzoate
H
2
O
CoA
ATP
2-
Succinylbenzoyl-
CoA
PP
i
AMP
H
+
H
2
O
1,4-
dihydroxy-2-
naphthoyl-CoA
H
2
O
CoA
H
+
1,4-
dihydroxy-2-
naphthoate
Octaprenyl
diphosphate
H
+
CO
2
PP
i
2-
Demethylmenaquinol
8
S-
Adenosylmethionine
H
+
S-
Adenosylhomocysteine
Menaquinol 8
H
+
Farnesylfarnesylgeranyl-
PP
CO
2
PP
i
H
+
Hydrogen
2-
Demethylmenaquinone
8
H
+
Endocytosis
entC
menD
menH
menC
menE
menB
menI
menA
ubiE
menA
hyaA
hyaB
hyaC
Chorismate
isochorismate
Oxoglutaric
acid
Hydrogen Ion
Carbon dioxide
2-succinyl-5-
enolpyruvyl-
6-hydroxy-3-
cyclohexene-
1-carboxylate
(1R,6R)-6-
hydroxy-2-
succinylcyclohexa-
2,4-diene-1-
carboxylate
Pyruvic acid
2-
succinylbenzoate
Water
Coenzyme A
Adenosine
triphosphate
2-
Succinylbenzoyl-
CoA
Pyrophosphate
Adenosine
monophosphate
Hydrogen Ion
Water
1,4-
dihydroxy-2-
naphthoyl-CoA
Water
Coenzyme A
Hydrogen Ion
1,4-
dihydroxy-2-
naphthoate
Octaprenyl
diphosphate
Hydrogen Ion
Carbon dioxide
Pyrophosphate
2-
Demethylmenaquinol
8
S-
Adenosylmethionine
Hydrogen Ion
S-
Adenosylhomocysteine
Menaquinol 8
Hydrogen Ion
Farnesylfarnesylgeranyl-
PP
Carbon dioxide
Pyrophosphate
Hydrogen Ion
Hydrogen
2-
Demethylmenaquinone
8
Hydrogen Ion
Endocytosis