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Spermidine/putrescine
import
ATP-binding
protein PotA
Spermidine/putrescine
transport
system permease
protein potB
Spermidine/putrescine
transport
system permease
protein potC
Spermidine/putrescine-
binding
periplasmic
protein
Gamma-
glutamylputrescine
synthetase
Gamma-
glutamylputrescine
oxidoreductase
Gamma-
glutamyl-
gamma-
aminobutyrate
hydrolase
Gamma-
glutamyl-
gamma-
aminobutyraldehyde
dehydrogenase
Putrescine
Putrescine
L-Glutamic acid
ATP
γ-glutamyl-L-
putrescine
ADP
H
+
P
i
O
2
H
+
γ-Glutamyl-γ-
butyraldehyde
H
2
O
2
Ammonium
γ-glutamyl-γ-
aminobutyrate
H
2
O
γ-Aminobutyric
acid
L-Glutamic acid
NADP
H
2
O
NADPH
H
+
ATP
H
2
O
ADP
P
i
H
+
potA
potB
potC
potD
puuA
puuB
puuD
puuC
Putrescine
Putrescine
L-Glutamic acid
Adenosine
triphosphate
γ-glutamyl-L-
putrescine
Adenosine
diphosphate
Hydrogen Ion
Phosphate
Oxygen
Hydrogen Ion
γ-Glutamyl-γ-
butyraldehyde
Hydrogen
peroxide
Ammonium
γ-glutamyl-γ-
aminobutyrate
Water
γ-Aminobutyric
acid
L-Glutamic acid
NADP
Water
NADPH
Hydrogen Ion
Adenosine
triphosphate
Water
Adenosine
diphosphate
Phosphate
Hydrogen Ion
potA
potB
potC
potD
puuA
puuB
puuD
puuC
Putrsce
Putrsce
Glu
ATP
γGLUPUT
ADP
H
+
P
i
O
2
H
+
gGgBra
H
2
O
2
Ammon
γGγA
H
2
O
GABA
Glu
NADP
H
2
O
NADPH
H
+
ATP
H
2
O
ADP
P
i
H
+