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Arginase,
mitochondrial
Ornithine
aminotransferase,
mitochondrial
Aldehyde
dehydrogenase
2,
mitochondrial
Glutamate
dehydrogenase,
mitochondrial
glutamate
synthase
NADP-dependent
glutamate
dehydrogenase
NADP-dependent
glutamate
dehydrogenase 2
Glutamate
dehydrogenase,
mitochondrial
Glutamate
decarboxylase
4-aminobutyrate
aminotransferase
succinate
semialdehyde
dehydrogenase 2
Oxoglutaric
acid
L-Arginine
H
2
O
Ornithine
Urea
Oxoglutaric
acid
L-Glutamic acid
L-Glutamic
γ-semialdehyde
NAD
H
2
O
H
+
NADH
L-Glutamic acid
H
2
O
NAD
Ammonium
NADH
H
+
L-Glutamine
Oxoglutaric
acid
H
+
NADH
L-Glutamic acid
NAD
NADPH
Ammonium
H
+
Oxoglutaric
acid
H
2
O
NADP
Oxoglutaric
acid
Ammonium
NADPH
H
+
H
2
O
NADP
H
2
O
NAD
Ammonium
NADH
H
+
Oxoglutaric
acid
H
+
CO
2
4-
(Glutamylamino)
butanoate
Oxoglutaric
acid
L-Glutamic acid
Succinic acid
semialdehyde
H
2
O
NADP
NADPH
Succinic acid
H
+
TCA Cycle
Endocytosis
Mitochondrion
CAR1
CAR2
ALD2
GDH2
GLT1
GDH1
GDH3
GDH2
GAD1
UGA1
UGA2
Oxoglutaric
acid
L-Arginine
Water
Ornithine
Urea
Oxoglutaric
acid
L-Glutamic acid
L-Glutamic
γ-semialdehyde
NAD
Water
Hydrogen Ion
NADH
L-Glutamic acid
Water
NAD
Ammonium
NADH
Hydrogen Ion
L-Glutamine
Oxoglutaric
acid
Hydrogen Ion
NADH
L-Glutamic acid
NAD
NADPH
Ammonium
Hydrogen Ion
Oxoglutaric
acid
Water
NADP
Oxoglutaric
acid
Ammonium
NADPH
Hydrogen Ion
Water
NADP
Water
NAD
Ammonium
NADH
Hydrogen Ion
Oxoglutaric
acid
Hydrogen Ion
Carbon dioxide
4-
(Glutamylamino)
butanoate
Oxoglutaric
acid
L-Glutamic acid
Succinic acid
semialdehyde
Water
NADP
NADPH
Succinic acid
Hydrogen Ion
TCA Cycle
Endocytosis
CAR1
CAR2
ALD2
GDH2
GLT1
GDH1
GDH3
GDH2
GAD1
UGA1
UGA2
AKG
Arg
H
2
O
Ornithi
Urea
AKG
Glu
L-Gl-GA
NAD
H
2
O
H
+
NADH
Glu
H
2
O
NAD
Ammon
NADH
H
+
Gln
AKG
H
+
NADH
Glu
NAD
NADPH
Ammon
H
+
AKG
H
2
O
NADP
AKG
Ammon
NADPH
H
+
H
2
O
NADP