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3-ketoacyl-CoA synthase ELO1 Acyl-CoA synthase Acyl-CoA synthase Acyl-CoA synthase Acyl-CoA synthase Acyl-CoA synthase 3-oxoacyl- [acyl- carrier- protein] reductase Peroxisomal hydratase- dehydrogenase- epimerase dihydrosphingosine C-4 hydroxylase 3- ketosphinganine reductase Ceramide synthase subunit LIP1 Serine palmitoyltransferase 1 2-enoyl thioester reductase Palmityl-CoA Malonyl-CoA H+ CO2 3- Oxooctadecanoyl- CoA CoA Palmitic acid ATP CoA AMP PPi H+ NADPH NADP (3R)-3- hydroxy- stearoyl-CoA (2E)- Octadecenoyl- CoA H2O H+ O2 Sphinganine H2O Phytosphingosine H+ NADPH 3- Dehydrosphinganine NADP Stearoyl-CoA CoA H+ N- stearoylphytosphingosine Palmityl-CoA L-Serine CO2 H+ NADPH NADP ferrocytochrome b5 ferricytochrome b5
Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown LIP1 LCB1 Unknown Palmityl-CoA Malonyl-CoA Hydrogen Ion Carbon dioxide 3- Oxooctadecanoyl- CoA Coenzyme A Palmitic acid Adenosine triphosphate Coenzyme A Adenosine monophosphate Pyrophosphate Hydrogen Ion NADPH NADP (3R)-3- hydroxy- stearoyl-CoA (2E)- Octadecenoyl- CoA Water Hydrogen Ion Oxygen Sphinganine Water Phytosphingosine Hydrogen Ion NADPH 3- Dehydrosphinganine NADP Stearoyl-CoA Coenzyme A Hydrogen Ion N- stearoylphytosphingosine Palmityl-CoA L-Serine Carbon dioxide Hydrogen Ion NADPH NADP ferrocytochrome b5 ferricytochrome b5