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Protein URA2
Protein URA2
Protein URA2
aspartate
transcarbamylase
Dihydroorotase
orotidine-5'-
phosphate
decarboxylase
UMP kinase
nucleoside
diphosphate
kinase
CTP synthase
ribonucleoside
diphosphate
reductase 1
Ribonucleoside-
diphosphate
reductase large
chain 1
ribonucleoside
diphosphate
reductase 1
ribonucleoside
diphosphate
reductase 1
nucleoside
diphosphate
kinase
deoxyuridine
triphosphatase
nucleoside
triphosphate
pyrophosphohydrolase
pyrimidine
deoxynucleoside
triphosphate
pyrophosphohydrolase
nucleoside
diphosphate
kinase
ribonucleoside-
triphosphate
reductase
dihydroorotate
dehydrogenase,
type 2
Thymidylate
synthase
Orotate
phosphoribosyltransferase
2
ribonucleoside-
diphosphate
reductase 2
ribonucleoside-
diphosphate
reductase 2
nucleoside
diphosphate
kinase
ribonucleoside-
triphosphate
reductase
dCTP deaminase
Ribonucleoside-
diphosphate
reductase large
chain 1
Ribonucleoside-
diphosphate
reductase small
chain 2
Thymidylate
kinase
L-Glutamine
Phosphoribosyl
pyrophosphate
HCO
3
-
H
2
O
ATP
ADP
P
i
L-Glutamic acid
H
+
Carbamoyl
phosphate
L-Aspartic acid
P
i
H
+
N-carbamoyl-
L-aspartate
H
+
H
2
O
4,5-
Dihydroorotic
acid
Orotidylic acid
H
+
CO
2
Uridine 5'-
monophosphate
ATP
ADP
Uridine
5'-diphosphate
ATP
Uridine
triphosphate
ADP
L-Glutamine
H
2
O
ATP
ADP
H
+
P
i
L-Glutamic acid
Cytidine
triphosphate
H
2
O
P
i
H
+
CDP
H
2
O
dCDP
H
2
O
dUDP
ATP
ADP
Deoxyuridine
triphosphate
H
2
O
P
i
H
+
dUMP
ATP
dTDP
ADP
Thymidine
5'-triphosphate
H
2
O
dCTP
Ubiquinone-1
Ubiquinol-1
Orotic acid
5,10-
methenyltetrahydrofolate
mono-L-
glutamate
Dihydrofolic
acid
5-Thymidylic
acid
PP
i
H
2
O
ATP
ADP
H
2
O
H
2
O
H
+
Ammonium
H
2
O
ATP
ADP
Adenosine
triphosphate
Zinc
Magnesium
Magnesium
Adenosine
triphosphate
Fe2+
Magnesium
Magnesium
Zinc
Magnesium
Magnesium
Adenosine
triphosphate
dGTP
Thymidine
5'-triphosphate
Potassium
Magnesium
Zinc (II) ion
4Fe-4S
Flavin
Mononucleotide
Magnesium
Adenosine
triphosphate
dGTP
Thymidine
5'-triphosphate
Potassium
Magnesium
Zinc (II) ion
4Fe-4S
Fe3+
reduced
thioredoxin
oxidized
thioredoxin
reduced
thioredoxin
oxidized
thioredoxin
a reduced
flavodoxin
an oxidized
flavodoxin
an oxidized
NrdH
glutaredoxin-
like protein
a reduced
flavodoxin
an oxidized
flavodoxin
a reduced NrdH
glutaredoxin-
like protein
an oxidized
NrdH
glutaredoxin-
like protein
L-Glutamate
Metabolism
PRPP
Biosynthesis
a reduced NrdH
glutaredoxin-
like protein
Guanosine
triphosphate
Magnesium