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Amiloride-
sensitive
sodium channel
subunit alpha
Amiloride-
sensitive
sodium channel
subunit beta
Amiloride-
sensitive
sodium channel
subunit alpha
Amiloride-
sensitive
sodium channel
subunit gamma
Sodium/potassium-
transporting
ATPase subunit
alpha-1
Sodium/potassium-
transporting
ATPase subunit
alpha-2
Sodium/potassium-
transporting
ATPase subunit
alpha-3
Sodium/potassium-
transporting
ATPase subunit
alpha-4
Sodium/potassium-
transporting
ATPase subunit
beta-1
Sodium/potassium-
transporting
ATPase subunit
beta-2
Sodium/potassium-
transporting
ATPase subunit
beta-3
Unknown
Sodium/potassium-
transporting
ATPase subunit
gamma
Solute carrier
family 12
member 3
Chloride
channel protein
ClC-Ka
Chloride
channel protein
ClC-Ka
Amiloride-
sensitive
sodium channel
subunit alpha
Amiloride-
sensitive
sodium channel
subunit beta
Amiloride-
sensitive
sodium channel
subunit alpha
Amiloride-
sensitive
sodium channel
subunit gamma
Excitatory
amino acid
transporter 3
Large neutral
amino acids
transporter
small subunit 2
4F2
cell-surface
antigen heavy
chain
Large neutral
amino acids
transporter
small subunit 1
4F2
cell-surface
antigen heavy
chain
Sodium- and
chloride-
dependent
transporter
XTRP3A
Sodium-coupled
neutral amino
acid
transporter 4
Y+L amino acid
transporter 1
4F2
cell-surface
antigen heavy
chain
Y+L amino acid
transporter 2
4F2
cell-surface
antigen heavy
chain
Neutral and
basic amino
acid transport
protein rBAT
b(0,+)-type
amino acid
transporter 1
Urea
transporter 2
Urea
transporter 2
Mineralocorticoid
receptor
Cl-
Cl-
Na+
Na+
Na+
K+
K+
Cl-
Cl-
H2 O
H2 O
H2 O
Na+
Na+
K+
K+
Cl-
Cl-
Cl-
Cl-
Na+
K+
K+
Cl-
Cl-
K+
K+
H2 O
H2 O
H2 O
H2 O
Na+
Na+
Na+
Na+
K+
K+
Na+
Na+
Na+
Na+
Cl-
Cl-
Na+
Na+
Na+
Na+
Na+
Na+
Urea
Urea
Hydrogen
carbonate
Hydrogen
carbonate
Hydrogen
carbonate
Hydrogen
carbonate
L-Cysteine
L-Cysteine
Urea
Aldosterone
Organic Anion
Organic Anion
Organic Cation
Organic Cation
L-Amino acid
L-Amino acid
Large Neutral
Amino Acids
Large Neutral
Amino Acids
Large Neutral
Amino Acids
Large Neutral
Amino Acids
Imino acids
Imino acids
L-Amino acid
L-Amino acid
L-Amino acid
L-Amino acid
L-Amino acid
L-Amino acid
Transcription/Translation
PROXIMAL CONVOLUTED TUBULE
LUMEN
INTERSTITIUM
BLADDER
DISTAL CONVOLUTED TUBULE
LUMEN
INTERSTITIUM
DESCENDING LIMB OF LOOP OF
HENLE
LUMEN
INTERSTITIUM
THICK ASCENDING LIMB OF LOOP
OF HENLE
LUMEN
LUMEN
INTERSTITIUM
COLLECTING TUBULE
INTERSTITIUM
Nucleus
Scnn1a
Scnn1b
Scnn1a
Scnn1g
Atp1a1
Atp1a2
Atp1a3
Atp1a4
Atp1b1
Atp1b2
Atp1b3
Unknown
Fxyd2
Slc12a3
Clcnka
Clcnka
Scnn1a
Scnn1b
Scnn1a
Scnn1g
Slc1a1
Slc7a8
Slc3a2
Slc7a5
Slc3a2
Slc6a20a
Slc38a4
Slc7a7
Slc3a2
Slc7a6
Slc3a2
Slc3a1
Slc7a9
Slc14a2
Slc14a2
Nr3c2
Chloride ion
Chloride ion
Sodium
Sodium
Sodium
Potassium
Potassium
Chloride ion
Chloride ion
Water
Water
Water
Sodium
Sodium
Potassium
Potassium
Chloride ion
Chloride ion
Chloride ion
Chloride ion
Sodium
Potassium
Potassium
Chloride ion
Chloride ion
Potassium
Potassium
Water
Water
Water
Water
Sodium
Sodium
Sodium
Sodium
Potassium
Potassium
Sodium
Sodium
Sodium
Sodium
Chloride ion
Chloride ion
Sodium
Sodium
Sodium
Sodium
Sodium
Sodium
Urea
Urea
Hydrogen
carbonate
Hydrogen
carbonate
Hydrogen
carbonate
Hydrogen
carbonate
L-Cysteine
L-Cysteine
Urea
Aldosterone
Organic Anion
Organic Anion
Organic Cation
Organic Cation
L-Amino acid
L-Amino acid
Large Neutral
Amino Acids
Large Neutral
Amino Acids
Large Neutral
Amino Acids
Large Neutral
Amino Acids
Imino acids
Imino acids
L-Amino acid
L-Amino acid
L-Amino acid
L-Amino acid
L-Amino acid
L-Amino acid
Transcription/Translation
Scnn1a
Scnn1b
Scnn1a
Scnn1g
Atp1a1
Atp1a2
Atp1a3
Atp1a4
Atp1b1
Atp1b2
Atp1b3
Fxyd2
Slc12a3
Clcnka
Clcnka
Scnn1a
Scnn1b
Scnn1a
Scnn1g
Slc1a1
Slc7a8
Slc3a2
Slc7a5
Slc3a2
Slc6a20a
Slc38a4
Slc7a7
Slc3a2
Slc7a6
Slc3a2
Slc3a1
Slc7a9
Slc14a2
Slc14a2
Nr3c2
Cl-
Cl-
Na+
Na+
Na+
K+
K+
Cl-
Cl-
H2 O
H2 O
H2 O
Na+
Na+
K+
K+
Cl-
Cl-
Cl-
Cl-
Na+
K+
K+
Cl-
Cl-
K+
K+
H2 O
H2 O
H2 O
H2 O
Na+
Na+
Na+
Na+
K+
K+
Na+
Na+
Na+
Na+
Cl-
Cl-
Na+
Na+
Na+
Na+
Na+
Na+
Urea
Urea
HCO3
HCO3
HCO3
HCO3
Cys
Cys
Urea
Aldostr
OA
OA
OC
OC
LAA
LAA
LNAA
LNAA
LNAA
LNAA
IA
IA
LAA
LAA
LAA
LAA
LAA
LAA
PW000455
PROXIMAL CONVOLUTED TUBULE
LUMEN
INTERSTITIUM
BLADDER
DISTAL CONVOLUTED TUBULE
LUMEN
INTERSTITIUM
DESCENDING LIMB OF LOOP OF
HENLE
LUMEN
INTERSTITIUM
THICK ASCENDING LIMB OF LOOP
OF HENLE
LUMEN
LUMEN
INTERSTITIUM
COLLECTING TUBULE
INTERSTITIUM
Nucleus
Scnn1a
Scnn1b
Scnn1a
Scnn1g
Atp1a1
Atp1a2
Atp1a3
Atp1a4
Atp1b1
Atp1b2
Atp1b3
Fxyd2
Slc12a3
Clcnka
Clcnka
Scnn1a
Scnn1b
Scnn1a
Scnn1g
Slc1a1
Slc7a8
Slc3a2
Slc7a5
Slc3a2
Slc6a20a
Slc38a4
Slc7a7
Slc3a2
Slc7a6
Slc3a2
Slc3a1
Slc7a9
Slc14a2
Slc14a2
Nr3c2
Cl
Cl
Na+
Na+
Na+
K+
K+
Cl
Cl
H2O
H2O
H2O
Na+
Na+
K+
K+
Cl
Cl
Cl
Cl
Na+
K+
K+
Cl
Cl
K+
K+
H2O
H2O
H2O
H2O
Na+
Na+
Na+
Na+
K+
K+
Na+
Na+
Na+
Na+
Cl
Cl
Na+
Na+
Na+
Na+
Na+
Na+
Urea
Urea
HCO3
HCO3
HCO3
HCO3
Cys
Cys
Urea
Aldostr
OA
OA
OC
OC
LAA
LAA
LNAA
LNAA
LNAA
LNAA
IA
IA
LAA
LAA
LAA
LAA
LAA
LAA
PW000455