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Malate
dehydrogenase,
mitochondrial
Malate
dehydrogenase,
mitochondrial
Serine/threonine-
protein kinase
mTOR
Hypoxia-inducible
factor 1-alpha
inhibitor
Myc
proto-oncogene
protein
Mitochondrial
pyruvate
carrier 1
Mitochondrial
pyruvate
carrier 1
Neutral amino
acid
transporter
B(0)
Neutral amino
acid
transporter A
Sodium-coupled
neutral amino
acid
transporter 5
C-Myc-binding
protein
Monocarboxylate
transporter 1
Y+L amino acid
transporter 1
Pyruvate
dehydrogenase
complex
Citrate synthase,
mitochondrial
Isocitrate
dehydrogenase
[NAD] subunit
alpha,
mitochondrial
Isocitrate
dehydrogenase
[NAD] subunit
beta,
mitochondrial
Isocitrate
dehydrogenase
[NAD] subunit
gamma,
mitochondrial
Oxoglutarate
dehydrogenase
complex
Succinyl-CoA
ligase
Fumarate
hydratase,
mitochondrial
Pyruvate
carboxylase,
mitochondrial
Aconitate
hydratase,
mitochondrial
Aconitate
hydratase,
mitochondrial
Succinate
dehydrogenase
[ubiquinone]
cytochrome b
small subunit,
mitochondrial
Succinate
dehydrogenase
cytochrome b560
subunit,
mitochondrial
Succinate
dehydrogenase
[ubiquinone]
iron-sulfur
subunit,
mitochondrial
Succinate
dehydrogenase
[ubiquinone]
flavoprotein
subunit,
mitochondrial
Pyruvate
dehydrogenase
complex
Citrate synthase,
mitochondrial
Fumarate
hydratase,
mitochondrial
Pyruvate
carboxylase,
mitochondrial
Aconitate
hydratase,
mitochondrial
Aconitate
hydratase,
mitochondrial
Succinate
dehydrogenase
[ubiquinone]
cytochrome b
small subunit,
mitochondrial
Succinate
dehydrogenase
cytochrome b560
subunit,
mitochondrial
Succinate
dehydrogenase
[ubiquinone]
iron-sulfur
subunit,
mitochondrial
Succinate
dehydrogenase
[ubiquinone]
flavoprotein
subunit,
mitochondrial
Glutaminase liver
isoform,
mitochondrial
Glutamate
dehydrogenase 1,
mitochondrial
Aspartate
aminotransferase,
mitochondrial
Unknown
Unknown
NADP-dependent
malic enzyme
L-lactate
dehydrogenase A
chain
Isocitrate
dehydrogenase
[NADP],
mitochondrial
ATP-citrate
synthase
ATP-citrate
synthase
Pyruvic acid
FADH2
Pyruvic acid
FADH2
Pyruvic acid
Pyruvic acid
L-Glutamine
L-Glutamine
L-Glutamine
L-Glutamine
L-Lactic acid
L-Lactic acid
L-Glutamine
L-Glutamine
L-Leucine
L-Leucine
CoA
NAD
Acetyl-CoA
CO2
NADH
H2 O
Oxalacetic acid
Citric acid
CoA
Isocitric acid
NAD
Oxoglutaric acid
CO2
NADH
H+
NAD
CoA
Succinyl-CoA
NADH
H+
CO2
Pi
GDP
CoA
GTP
L-Malic acid
Fumaric acid
H2 O
NAD
NADH
H+
ATP
HCO3 -
ADP
Pi
cis-Aconitic acid
H2 O
H2 O
Q
FAD
FADH2
Fumaric acid
QH2
CoA
NAD
Acetyl-CoA
CO2
NADH
H2 O
Oxalacetic acid
Citric acid
CoA
L-Malic acid
Fumaric acid
H2 O
NAD
NADH
H+
ATP
HCO3 -
ADP
Pi
cis-Aconitic acid
H2 O
H2 O
Isocitric acid
Q
FAD
FADH2
Fumaric acid
QH2
L-Glutamic acid
NH3
NAD
NADH
Hydrogen Ion
Oxoglutaric acid
Oxalacetic acid
Oxoglutaric acid
L-Aspartic acid
Pyruvic acid
Oxoglutaric acid
L-Alanine
NADP
NADPH
H+
CO2
Pyruvic acid
NADH
H+
NAD
CO2
Citric acid
CoA
ATP
Oxalacetic acid
ADP
Acetyl-CoA
CoA
ATP
Oxalacetic acid
ADP
Acetyl-CoA
Oxygen
L-Glutamine
Thiamine
pyrophosphate
Lipoamide
FAD
Magnesium
Thiamine
pyrophosphate
Lipoamide
FAD
Biotin
Manganese
4Fe-4S
4Fe-4S
Thiamine
pyrophosphate
Lipoamide
FAD
Biotin
Manganese
4Fe-4S
4Fe-4S
Pyridoxal
5'-phosphate
Manganese
4Fe-4S
Aconitate
hydratase,
mitochondrial
Glycolysis
Mitochondrial
Electron
Transport Chain
Glycolysis
Mitochondrial
Electron
Transport Chain
Succinic acid
Inner mitochondrial membrane
Mitochondrial intermembrane
space
Cytosol
Mitochondrial matrix
Mitochondrion
Intracellular Space
Inner mitochondrial membrane
Outer mitochondrial membrane
Inner mitochondrial membrane
Mitochondrial intermembrane
space
Cytosol
Mitochondrial matrix
Mitochondrion
Intracellular Space
Inner mitochondrial membrane
Outer mitochondrial membrane
Pseudo-Hypoxia
Mutant Aconitase
Mutant Aconitase
Lipid Synthesis
Mitochondria
Mitochondria
MDH2
MDH2
MTOR
HIF1AN
MYC
MPC1
MPC1
SLC1A5
SLC1A4
SLC38A5, SN2
MYCBP
SLC16A1
SLC7A7
PDHA1
CS
IDH3A
IDH3B
IDH3G
OGDH
SUCLG1
SUCLG2
FH
PC
ACO2
ACO2
SDHD
SDHC
SDHB
SDHA
PDHA1
CS
FH
PC
ACO2
ACO2
SDHD
SDHC
SDHB
SDHA
GLS2
GLUD1
GOT2
Unknown
Unknown
ME1
LDHA
IDH2
ACLY
ACLY
Pyruvic acid
FADH
Pyruvic acid
FADH
Pyruvic acid
Pyruvic acid
L-Glutamine
L-Glutamine
L-Glutamine
L-Glutamine
L-Lactic acid
L-Lactic acid
L-Glutamine
L-Glutamine
L-Leucine
L-Leucine
Coenzyme A
NAD
Acetyl-CoA
Carbon dioxide
NADH
Water
Oxalacetic acid
Citric acid
Coenzyme A
Isocitric acid
NAD
Oxoglutaric acid
Carbon dioxide
NADH
Hydrogen Ion
NAD
Coenzyme A
Succinyl-CoA
NADH
Hydrogen Ion
Carbon dioxide
Phosphate
Guanosine
diphosphate
Coenzyme A
Guanosine
triphosphate
L-Malic acid
Fumaric acid
Water
NAD
NADH
Hydrogen Ion
Adenosine
triphosphate
Hydrogen
carbonate
Adenosine
diphosphate
Phosphate
cis-Aconitic acid
Water
Water
Coenzyme Q10
FAD
FADH
Fumaric acid
QH2
Coenzyme A
NAD
Acetyl-CoA
Carbon dioxide
NADH
Water
Oxalacetic acid
Citric acid
Coenzyme A
L-Malic acid
Fumaric acid
Water
NAD
NADH
Hydrogen Ion
Adenosine
triphosphate
Hydrogen
carbonate
Adenosine
diphosphate
Phosphate
cis-Aconitic acid
Water
Water
Isocitric acid
Coenzyme Q10
FAD
FADH
Fumaric acid
QH2
L-Glutamic acid
Ammonia
NAD
NADH
Hydrogen Ion
Oxoglutaric acid
Oxalacetic acid
Oxoglutaric acid
L-Aspartic acid
Pyruvic acid
Oxoglutaric acid
L-Alanine
NADP
NADPH
Hydrogen Ion
Carbon dioxide
Pyruvic acid
NADH
Hydrogen Ion
NAD
Carbon dioxide
Citric acid
Coenzyme A
Adenosine
triphosphate
Oxalacetic acid
Adenosine
diphosphate
Acetyl-CoA
Coenzyme A
Adenosine
triphosphate
Oxalacetic acid
Adenosine
diphosphate
Acetyl-CoA
Oxygen
L-Glutamine
ACO2
Glycolysis
Mitochondrial
Electron
Transport Chain
Glycolysis
Mitochondrial
Electron
Transport Chain
Succinic acid