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Bifunctional
protein glmU
Beta-
hexosaminidase
N-
acetylmuramoyl-
L-alanine amidase
AmiD
Anhydro-N-
acetylmuramic
acid kinase
N-acetylmuramic
acid 6-phosphate
etherase
N-
acetylglucosamine-
6-phosphate
deacetylase
Phosphoglucosamine
mutase
Bifunctional
protein glmU
D-glucosamine
6-phosphate
GlcNAc-1,6-
anhMurNAc-L-
Ala-?-D-Glu-
DAP-D-Ala
GlcNAc-1,6-
anhMurNAc-L-
Ala-?-D-Glu-
DAP-D-Ala
H+
H+
N-acetyl-β-D-
glucosamine(anhydrous)-
N- acetylmuramate
H2 O
N-Acetyl-D-
glucosamine
1,6-anhydro-N-
acetyl-β-
muramate
H2 O
L-Ala-γ-D-Glu-
DAP-D-Ala
ATP
H2 O
N-Acetylmuramate
6-phosphate
ADP
H+
H2 O
N-Acetyl-D-
Glucosamine
6-Phosphate
D-Lactic acid
H2 O
Acetic acid
Glucosamine-1P
Acetyl-CoA
N-Acetyl-
glucosamine
1-phosphate
CoA
H+
Uridine
triphosphate
H+
Uridine
diphosphate-N-
acetylglucosamine
diphosphate
N-
Acetylneuraminate,
N-
Acetylmannosamine,
and N-
Acetylglucosamine
Degradation
Lipopolysaccharide
Biosynthesis
Protein AmpG
1,6-anhydro-N-
acetylmuramyl-
L-alanine amidase
AmpD
glmU
nagZ
amiD
anmK
murQ
nagA
glmM
glmU
D-glucosamine
6-phosphate
GlcNAc-1,6-
anhMurNAc-L-
Ala-?-D-Glu-
DAP-D-Ala
GlcNAc-1,6-
anhMurNAc-L-
Ala-?-D-Glu-
DAP-D-Ala
Hydrogen Ion
Hydrogen Ion
N-acetyl-β-D-
glucosamine(anhydrous)-
N- acetylmuramate
Water
N-Acetyl-D-
glucosamine
1,6-anhydro-N-
acetyl-β-
muramate
Water
L-Ala-γ-D-Glu-
DAP-D-Ala
Adenosine
triphosphate
Water
N-Acetylmuramate
6-phosphate
Adenosine
diphosphate
Hydrogen Ion
Water
N-Acetyl-D-
Glucosamine
6-Phosphate
D-Lactic acid
Water
Acetic acid
Glucosamine-1P
Acetyl-CoA
N-Acetyl-
glucosamine
1-phosphate
Coenzyme A
Hydrogen Ion
Uridine
triphosphate
Hydrogen Ion
Uridine
diphosphate-N-
acetylglucosamine
diphosphate
N-
Acetylneuraminate,
N-
Acetylmannosamine,
and N-
Acetylglucosamine
Degradation
Lipopolysaccharide
Biosynthesis
ampG
ampD
glmU
nagZ
amiD
anmK
murQ
nagA
glmM
glmU
DG6P
G16ALA
G16ALA
H+
H+
NAβDGAN
H2 O
GlcNAc
16ANAβM
H2 O
LADγDG
ATP
H2 O
M6P
ADP
H+
H2 O
NAcG6P
D-Lac
H2 O
Acoh
GluN-1P
Ac-CoA
NGluA1P
CoA
H+
UTP
H+
UDP-GN
PP2
PW002030
PW000831
ampG
ampD
glmU
nagZ
amiD
anmK
murQ
nagA
glmM
glmU
DG6P
G16ALA
G16ALA
H+
H+
NAβDGAN
H2O
GlcNAc
16ANAβM
H2O
LADγDG
ATP
H2O
M6P
ADP
H+
H2O
NAcG6P
D-Lac
H2O
Acoh
GluN-1P
Ac-CoA
NGluA1P
CoA
H+
UTP
H+
UDP-GN
PP2
PW002030
PW000831
ampG
ampD