Losartan, sometimes called Cozaar, is a medication used to treat hypertension, also know as hypertension. It works by preventing the mechanism of action that causes blood vessels to tighten. It acts as an angiotensin II receptor blocker, or an ARB. This means that it works by inhibiting the activation of angiotensin through the angiotensin II receptor. This prevents the subsequent activation of cytochrome P450 11B2, which in turn creates aldosterone. For this reason, Losartan can be used in the treatment of diabetes, as it can help prevent damage to the kidneys. Losartan has side effects such as headaches, dizziness, sleep disruptions, and diarrhea,

Losartan Action Pathway References