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Tryptophan 2,3-dioxygenase Kynureninase Kynurenine formamidase Kynurenine formamidase Kynureninase Kynurenine/alpha- aminoadipate aminotransferase, mitochondrial Kynurenine 3-monooxygenase Kynurenine/alpha- aminoadipate aminotransferase, mitochondrial Tryptophan 5-hydroxylase 1 Indoleamine 2,3-dioxygenase 1 Aromatic-L- amino-acid decarboxylase Kynurenine 3-monooxygenase Aldehyde dehydrogenase, mitochondrial Indoleamine 2,3-dioxygenase 1 Tryptophan-- tRNA ligase, cytoplasmic Tryptophan-- tRNA ligase, mitochondrial L-Tryptophan N'- Formylkynurenine Formylanthranilic acid L-Kynurenine 2-Aminobenzoic acid 4-(2- Aminophenyl)- 2,4- dioxobutanoic acid Kynurenic acid L-3- Hydroxykynurenine 4-(2-Amino-3- hydroxyphenyl)- 2,4- dioxobutanoic acid Xanthurenic acid 5-Hydroxy-L- tryptophan 5-Hydroxy-N- formylkynurenine Tryptamine Indoleacetaldehyde Indoleacetic acid Extracellular space Intracellular space Mitochondria
TDO2 KYNU AFMID AFMID KYNU AADAT KMO AADAT TPH1 IDO1 DDC KMO ALDH2 IDO1 WARS WARS2 L-Tryptophan N'- Formylkynurenine Formylanthranilic acid L-Kynurenine 2-Aminobenzoic acid 4-(2- Aminophenyl)- 2,4- dioxobutanoic acid Kynurenic acid L-3- Hydroxykynurenine 4-(2-Amino-3- hydroxyphenyl)- 2,4- dioxobutanoic acid Xanthurenic acid 5-Hydroxy-L- tryptophan 5-Hydroxy-N- formylkynurenine Tryptamine Indoleacetaldehyde Indoleacetic acid
TDO2 KYNU AFMID AFMID KYNU AADAT KMO AADAT TPH1 IDO1 DDC KMO ALDH2 IDO1 WARS WARS2 Trp Formylk Formyla L-Kynr 2AA 42A24D Kynuren L-3-HK 42A3H24 Xanthur 5-HTP 5HNFKN Tryptam Tryptal Indolaa Extracellular space Intracellular space Mitochondria
TDO2 KYNU AFMID AFMID KYNU AADAT KMO AADAT TPH1 IDO1 DDC KMO ALDH2 IDO1 WARS WARS2 Trp Formylk Formyla L-Kynr 2AA 42A24D Kynuren L-3-HK 42A3H24 Xanthur 5-HTP 5HNFKN Tryptam Tryptal Indolaa