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Malate
dehydrogenase,
mitochondrial
Methylcytosine
dioxygenase
TET1
Lysine-specific
demethylase 2A
Mitochondrial
pyruvate
carrier 1
Pyruvate
dehydrogenase
complex
Citrate
synthase,
mitochondrial
Isocitrate
dehydrogenase
[NAD] subunit
alpha,
mitochondrial
Isocitrate
dehydrogenase
[NAD] subunit
beta,
mitochondrial
Isocitrate
dehydrogenase
[NAD] subunit
gamma,
mitochondrial
Oxoglutarate
dehydrogenase
complex
Succinyl-CoA
ligase
Fumarate
hydratase,
mitochondrial
Pyruvate
carboxylase,
mitochondrial
Succinate
dehydrogenase
Aconitate
hydratase,
mitochondrial
Aconitate
hydratase,
mitochondrial
NADP-specific
glutamate
dehydrogenase
Glutaminase
liver isoform,
mitochondrial
Isocitrate
dehydrogenase
[NADP]
cytoplasmic
NADP+-specific
isocitrate
dehydrogenase
mutant
Isocitrate
dehydrogenase 2
[NADP],
mitochondrial
Isocitrate
dehydrogenase
[NADP],
mitochondrial
Cytoplasmic
aconitate
hydratase
Pyruvic acid
FADH2
Pyruvic acid
CoA
NAD
Acetyl-CoA
CO2
NADH
H2 O
Oxalacetic acid
Citric acid
CoA
Isocitric acid
NAD
Oxoglutaric acid
CO2
NADH
H+
NAD
CoA
Succinyl-CoA
NADH
H+
CO2
Pi
GDP
Succinic acid
CoA
GTP
L-Malic acid
Fumaric acid
H2 O
NAD
NADH
H+
ATP
HCO3 -
ADP
Pi
Q
FAD
QH2
cis-Aconitic
acid
H2 O
H2 O
NADPH
Ammonium
H+
L-Glutamic acid
H2 O
NADP
L-Glutamine
H2 O
NH3
Isocitric acid
NADP
Oxoglutaric acid
NADPH
NADPH
2-Hydroxyglutarate
NADP
NADP
Oxoglutaric acid
NADPH
NADP
NADPH
Citric acid
Thiamine
pyrophosphate
Lipoamide
FAD
Magnesium
Thiamine
pyrophosphate
Lipoamide
FAD
Biotin
Manganese
4Fe-4S
4Fe-4S
Magnesium
4Fe-4S
Glycolysis
Mitochondrial
Electron
Transport Chain
Inner mitochondrial membrane
Mitochondrial intermembrane
space
Cytosol
Mitochondrial matrix
Mitochondrion
Intracellular Space
Inner mitochondrial membrane
Outer mitochondrial membrane
Cytosol
Epigenetic Regulation
Oncogene Activation,
Tumour-suppressor
inactivation
TCA cycle
Citric acid
Isocitric acid
Oxoglutaric acid
2-Hydroxyglutarate
Cytoplasmic aconitate
hydratase
Isocitrate dehydrogenase
[NADP] cytoplasmic
mutIDH1
Methylcystosine dioxygenase
TET1
Lysine-specific demethylase
2A