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Feline leukemia virus subgroup C receptor- related protein 2 5- aminolevulinate synthase, nonspecific, mitochondrial Delta- aminolevulinic acid dehydratase Porphobilinogen deaminase Uroporphyrinogen- III synthase Uroporphyrinogen decarboxylase Uroporphyrinogen decarboxylase Coproporphyrinogen- III oxidase, mitochondrial Ferritin, mitochondrial Ferrochelatase, mitochondrial Protoheme IX farnesyltransferase, mitochondrial Cytochrome c oxidase assembly protein COX15 homolog Biliverdin reductase A UDP- glucuronosyltransferase 2B11 Beta- glucuronidase Protoporphyrinogen oxidase Heme oxygenase 1 Glycine Coproporphyrinogen III Coproporphyrinogen III Protoporphyrin IX Protoporphyrin IX Heme Heme Succinyl-CoA 5-Aminolevulinic acid CO2 Porphobilinogen H2O H2O Hydroxymethylbilane NH3 Uroporphyrinogen III H2O Uroporphyrin III Uroporphyrinogen I Coproporphyrinogen I CO2 Coproporphyrin I Uroporphyrin I CO2 Coproporphyrin III O2 H+ Protoporphyrinogen IX CO2 H2O Fe2+ H+ O2 Fe3+ H2O H+ Farnesyl pyrophosphate Heme O Heme A Biliverdin NAD Bilirubin NADH Uridine diphosphate glucuronic acid Bilirubin diglucuronide Uridine 5'-diphosphate H2O Urobilinogen O2 H2O2 O2 Fe2+ Carbon monoxide H2O Pyridoxal 5'-phosphate Zinc Zinc Alcohol AH2 A Intracellular Space Glycine and Serine Metabolism FAD 2Fe-2S Mitochondria Outer mitochondrial membrane Inner mitochondrial membrane Microsome Microsome Lysosome Symptoms of the disorder include abdominal pain, constipation, vomiting, hypertension, muscle weakness, seizures, delirium, coma, and depression. Hypertension
Mitochondria FLVCR2 ALAS1 ALAD HMBS UROS UROD UROD CPOX FTMT FECH COX10 COX15 BLVRA UGT2B11 GUSB PPOX HMOX1 Glycine Coproporphyrinogen III Coproporphyrinogen III Protoporphyrin IX Protoporphyrin IX Heme Heme Succinyl-CoA 5- Aminolevulinic acid Carbon dioxide Porphobilinogen Water Water Hydroxymethylbilane Ammonia Uroporphyrinogen III Water Uroporphyrin III Uroporphyrinogen I Coproporphyrinogen I Carbon dioxide Coproporphyrin I Uroporphyrin I Carbon dioxide Coproporphyrin III Oxygen Hydrogen Protoporphyrinogen IX Carbon dioxide Water Fe2+ Hydrogen Oxygen Fe3+ Water Hydrogen Farnesyl pyrophosphate Heme O Heme A Biliverdin NAD Bilirubin NADH Uridine diphosphate glucuronic acid Bilirubin diglucuronide Uridine 5'-diphosphate Water Urobilinogen Oxygen Hydrogen peroxide Oxygen Fe2+ Carbon monoxide Water Alcohol AH2 A Glycine and Serine Metabolism
FLVCR2 ALAS1 ALAD HMBS UROS UROD UROD CPOX FTMT FECH COX10 COX15 BLVRA UGT2B11 GUSB PPOX HMOX1 Gly Coprgn3 Coprgn3 PrtopIX PrtopIX Heme Heme Suc-CoA 5-Amnva CO2 PBG H2O H2O HMBilan NH3 Urppr3 H2O Urop3 Uropg1 CPPgen CO2 CopropI Urop1 CO2 CoprIII O2 H+ Protop9 CO2 H2O Fe2+ H+ O2 Fe3+ H2O H+ FarPP Heme O Heme A Bilvdn NAD BilRubn NADH UDPGlcA BRubnDG UDP H2O Urbilgn O2 H2O2 O2 Fe2+ CO H2O Pyr-5'P Zinc Zinc Alcohol AH2 A Intracellular Space PW000157 FAD 2Fe2S Mitochondria Outer mitochondrial membrane Inner mitochondrial membrane Microsome Microsome Lysosome Symptoms of the disorder include abdominal pain, constipation, vomiting, hypertension, muscle weakness, seizures, delirium, coma, and depression. Hypertension
Mitochondria FLVCR2 ALAS1 ALAD HMBS UROS UROD UROD CPOX FTMT FECH COX10 COX15 BLVRA UGT2B11 GUSB PPOX HMOX1 Gly Coprgn3 Coprgn3 PrtopIX PrtopIX Heme Heme Suc-CoA 5-Amnva CO2 PBG H2O H2O HMBilan NH3 Urppr3 H2O Urop3 Uropg1 CPPgen CO2 CopropI Urop1 CO2 CoprIII O2 H2 Protop9 CO2 H2O Fe2+ H2 O2 Fe3+ H2O H2 FarPP Heme O Heme A Bilvdn NAD BilRubn NADH UDPGlcA BRubnDG UDP H2O Urbilgn O2 H2O2 O2 Fe2+ CO H2O Alcohol AH2 A PW000157