Micafungin, also known as Mycamine, is an echinocandin antifungal agent used for the treatment of candidemia, acute disseminated candidiasis, and certain other fungal infections..More commonly, Micafungin is used against Aspergillus infections, and only used against some Candida infections. It is also used to treat the prophylaxis of Candida infections during stem cell transplantation. It is a glucan synthesis inhibitor which is essential for cell wall synthesis. Micafungin inhibits glucan synthase, an enzyme present in fungal, but not mammalian cells. This prevents the synthesis of 1,3-β-D-glucan, an essential component of the fungal cell wall, which ultimately leads to osmotic instability and cell death.

Micafungin Pathway References