Anistreplase is a plasminogen activator created from recombinant human tissue, used in emergencies such as myocardial infarction and pulmonary emboli. It is administered intravenously and travels throughout the bloodstream to target blood clots by activating plasminogen. Anistreplase converts plasminogen to its active form plasmin by cleaving an arginine-valine bond, plasmin then acts on the fibrin matrix of the blood clot breaking it down into degradation products. Due to its anticoagulant and antiplatelet activity, avoid herbs and supplements with similar activity such as garlic, ginger, bilberry, danshen, piracetam and ginkgo biloba.

Anistreplase Pathway (new) References