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Abciximab
Cystatin-B
Amino acids
Bowman's Capsule
Proximal Tubule
Loop of Henle
Distal Tubule
Collecting Duct
[BIOTECH DRUG] is
metabolized by the kidney,
through glomerular
filtration and extensive
reactions that leads to
either reabsorption or
elimination of the
byproducts
Majority is broken down by
proteases that are found
throughout the kidney
filtration system. Targeting
majority of the [BIOTECH
DRUG] in the proximal tubule
Glomerulus
Lumen
Blood
The fragments of [BIOTECH
DRUG] is reduced to amino
acids, which are then
reabsorbed via the
collecting duct to be used
in de novo protein synthesis
and other metabolic
pathways. All additional
byproducts in excess is
excreted via urine
Kidney
CSTB
AA
Bowman's Capsule
Proximal Tubule
Loop of Henle
Distal Tubule
Collecting Duct
[BIOTECH DRUG] is
metabolized by the kidney,
through glomerular
filtration and extensive
reactions that leads to
either reabsorption or
elimination of the
byproducts
Majority is broken down by
proteases that are found
throughout the kidney
filtration system. Targeting
majority of the [BIOTECH
DRUG] in the proximal tubule
Glomerulus
Lumen
Blood
The fragments of [BIOTECH
DRUG] is reduced to amino
acids, which are then
reabsorbed via the
collecting duct to be used
in de novo protein synthesis
and other metabolic
pathways. All additional
byproducts in excess is
excreted via urine
Kidney