Linezolid is a synthetic antibiotic, also known as Zyvox and Zyvoxam used to treat gram-positive bacteria. Linezolid is absorbed after oral administration and travels to the bacterial cell, it binds to the bacterial 23S ribosomal RNA of the 50S subunit preventing the 70S complex that is needed for reproduction. Linezolid is metabolized to aminoethoxyacetic acid and hydroxyethyl glycine and metabolites through oxidation. When taking linezolid foods and supplements containing tyramine such as cheese, red wine, fava beans, pickled foods, cured foods and alcoholic beverages.

Linezolid Pathway References