Sulfathiazole is a short-acting antibiotic from the sulfonamide drug class. This drug is mostly used with cattle because less toxic alternatives were discovered for humans. Except for vaginal use (vaginal cream), the FDA withdrew the approval of sulfathiazole products. This drug is active against a wide range of gram-positive and gram-negative bacteria. It was used for bacterial enteritis, bacterial pneumonia, ear infections, eye infections, skin ulcers, urinary tract infections, and many others. Sulfathiazole is an inhibitor of dihydropteroate synthase. This inhibition results in the inability of the bacteria to produce folic acid, thus the growth of the bacteria is inhibited (bacteriostatic).

Sulfathiazole Pathway References