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Pathway Description
Gadopentetic acid Metabolism
Homo sapiens
Metabolic Pathway
Gadopentetic acid is a gadolinium compound used as a contrast agent in MRIs. It is a complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA), that is given to enhance the image in cranial and spinal MRIs. It is used with magnetic resonance imaging (MRI) in adults, and pediatric patients (2 years of age and older) to visualize lesions with abnormal vascularity in the brain (intracranial lesions), spine and associated tissues as well as lesions with abnormal vascularity in the head and neck. Also used to facilitate the visualization of lesions with abnormal vascularity in the body (excluding the heart). No detectable biotransformation or decomposition have been reported.
References
Gadopentetic acid Metabolism References
Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M: DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037.
Pubmed: 29126136
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