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Pathway Description
Lasmiditan Mechanism of Action Action Pathway
Homo sapiens
Drug Action Pathway
Lasmiditan is an oral 5HT1F agonist used for the acute treatment of migraine headache with or without aura. The utility of this medication is that it lacks vasoconstrictor effects such as those seen in triptans, and thus offers those with cardiovascular disease an alternative to triptans.
References
Lasmiditan Mechanism of Action pathway References
Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M: DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037.
Pubmed: 29126136
Nicolas S, Nicolas D: Triptans.
Pubmed: 32119394
Lew C, Punnapuzha S: Migraine Medications.
Pubmed: 31985952
Pescador Ruschel MA, De Jesus O: Migraine Headache.
Pubmed: 32809622
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