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Cytochrome P450 3A4 Berotralstat Berotralstat Berotralstat PIS1M1 Berotralstat PIS1M1 Urinary Excretion and/or Bile duct Excretion Heme Hepatocytes Kidney Liver Cytosol Berotralstat undergoes metabolism to give Berotralstat PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Berotralstat Berotralstat Berotralstat PIS1M1 Berotralstat PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP3A4 Berot Berot Ber PIS Ber PIS U E a B Heme Hepatocytes Kidney Liver Cytosol Berotralstat undergoes metabolism to give Berotralstat PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Berot Berot Ber PIS Ber PIS U E a B