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Cytochrome P450 3A4 Dihydroergotamine Dihydroergotamine Dihydroergotamine PIS1M1 Dihydroergotamine PIS1M1 Urinary Excretion and/or Bile duct Excretion Heme Hepatocytes Kidney Liver Cytosol Dihydroergotamine undergoes metabolism to give Dihydroergotamine PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Dihydroergotamine Dihydroergotamine Dihydroergotamine PIS1M1 Dihydroergotamine PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP3A4 Dihydro Dihydro Dih PIS Dih PIS U E a B Heme Hepatocytes Kidney Liver Cytosol Dihydroergotamine undergoes metabolism to give Dihydroergotamine PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Dihydro Dihydro Dih PIS Dih PIS U E a B