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Cytochrome P450 3A4 Lasmiditan Lasmiditan Lasmiditan PIS1M1 Lasmiditan PIS1M1 Urinary Excretion and/or Bile duct Excretion Heme Hepatocytes Kidney Liver Cytosol Lasmiditan undergoes metabolism to give Lasmiditan PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Lasmiditan Lasmiditan Lasmiditan PIS1M1 Lasmiditan PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP3A4 Lasmi Lasmi Las PIS Las PIS U E a B Heme Hepatocytes Kidney Liver Cytosol Lasmiditan undergoes metabolism to give Lasmiditan PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Lasmi Lasmi Las PIS Las PIS U E a B