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Cytochrome P450 3A4 Maralixibat Maralixibat Maralixibat PIS1M1 Maralixibat PIS1M1 Urinary Excretion and/or Bile duct Excretion Heme Hepatocytes Kidney Liver Cytosol Maralixibat undergoes metabolism to give Maralixibat PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Maralixibat Maralixibat Maralixibat PIS1M1 Maralixibat PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP3A4 Maral Maral Mar PIS Mar PIS U E a B Heme Hepatocytes Kidney Liver Cytosol Maralixibat undergoes metabolism to give Maralixibat PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Maral Maral Mar PIS Mar PIS U E a B