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Cytochrome P450 3A4 Nitrendipine Nitrendipine Nitrendipine PIS1M1 Nitrendipine PIS1M1 Urinary Excretion and/or Bile duct Excretion Heme Hepatocytes Kidney Liver Cytosol Nitrendipine undergoes metabolism to give Nitrendipine PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Nitrendipine Nitrendipine Nitrendipine PIS1M1 Nitrendipine PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP3A4 Nitrend Nitrend Nit PIS Nit PIS U E a B Heme Hepatocytes Kidney Liver Cytosol Nitrendipine undergoes metabolism to give Nitrendipine PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Nitrend Nitrend Nit PIS Nit PIS U E a B