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Cytochrome P450 3A4 Paritaprevir Paritaprevir Paritaprevir PIS1M1 Paritaprevir PIS1M1 Urinary Excretion and/or Bile duct Excretion Heme Hepatocytes Kidney Liver Cytosol Paritaprevir undergoes metabolism to give Paritaprevir PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Paritaprevir Paritaprevir Paritaprevir PIS1M1 Paritaprevir PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP3A4 Parit Parit Par PIS Par PIS U E a B Heme Hepatocytes Kidney Liver Cytosol Paritaprevir undergoes metabolism to give Paritaprevir PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Parit Parit Par PIS Par PIS U E a B