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Cytochrome P450 3A4 Retapamulin Retapamulin Retapamulin PIS1M1 Retapamulin PIS1M1 Urinary Excretion and/or Bile duct Excretion Heme Hepatocytes Kidney Liver Cytosol Retapamulin undergoes metabolism to give Retapamulin PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Retapamulin Retapamulin Retapamulin PIS1M1 Retapamulin PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP3A4 Sb Sb Ret PIS Ret PIS U E a B Heme Hepatocytes Kidney Liver Cytosol Retapamulin undergoes metabolism to give Retapamulin PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Sb Sb Ret PIS Ret PIS U E a B