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Cytochrome P450 3A4 Rucaparib Rucaparib Rucaparib PIS1M1 Rucaparib PIS1M1 Urinary Excretion and/or Bile duct Excretion Heme Hepatocytes Kidney Liver Cytosol Rucaparib undergoes metabolism to give Rucaparib PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Rucaparib Rucaparib Rucaparib PIS1M1 Rucaparib PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP3A4 Rucap Rucap Ruc PIS Ruc PIS U E a B Heme Hepatocytes Kidney Liver Cytosol Rucaparib undergoes metabolism to give Rucaparib PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Rucap Rucap Ruc PIS Ruc PIS U E a B