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Cytochrome P450 3A4 Sulfadiazine Sulfadiazine Sulfadiazine PIS1M1 Sulfadiazine PIS1M1 Urinary Excretion and/or Bile duct Excretion Heme Hepatocytes Kidney Liver Cytosol Sulfadiazine undergoes metabolism to give Sulfadiazine PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Sulfadiazine Sulfadiazine Sulfadiazine PIS1M1 Sulfadiazine PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP3A4 Sda Sda Sul PIS Sul PIS U E a B Heme Hepatocytes Kidney Liver Cytosol Sulfadiazine undergoes metabolism to give Sulfadiazine PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Sda Sda Sul PIS Sul PIS U E a B