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Cytochrome P450 3A4 Sulfametopyrazine Sulfametopyrazine Sulfametopyrazine PIS1M1 Sulfametopyrazine PIS1M1 Urinary Excretion and/or Bile duct Excretion Heme Hepatocytes Kidney Liver Cytosol Sulfametopyrazine undergoes metabolism to give Sulfametopyrazine PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Sulfametopyrazine Sulfametopyrazine Sulfametopyrazine PIS1M1 Sulfametopyrazine PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP3A4 Sulfale Sulfale Sul PIS Sul PIS U E a B Heme Hepatocytes Kidney Liver Cytosol Sulfametopyrazine undergoes metabolism to give Sulfametopyrazine PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Sulfale Sulfale Sul PIS Sul PIS U E a B