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Cytochrome P450 3A4 Tizanidine Tizanidine Tizanidine PIS1M1 Tizanidine PIS1M1 Urinary Excretion and/or Bile duct Excretion Heme Hepatocytes Kidney Liver Cytosol Tizanidine undergoes metabolism to give Tizanidine PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Tizanidine Tizanidine Tizanidine PIS1M1 Tizanidine PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP3A4 Tizanid Tizanid Tiz PIS Tiz PIS U E a B Heme Hepatocytes Kidney Liver Cytosol Tizanidine undergoes metabolism to give Tizanidine PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Tizanid Tizanid Tiz PIS Tiz PIS U E a B