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Cytochrome P450 3A4 Tolmetin Tolmetin Tolmetin PIS1M1 Tolmetin PIS1M1 Urinary Excretion and/or Bile duct Excretion Heme Hepatocytes Kidney Liver Cytosol Tolmetin undergoes metabolism to give Tolmetin PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Tolmetin Tolmetin Tolmetin PIS1M1 Tolmetin PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP3A4 Tolmetn Tolmetn Tol PIS Tol PIS U E a B Heme Hepatocytes Kidney Liver Cytosol Tolmetin undergoes metabolism to give Tolmetin PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Tolmetn Tolmetn Tol PIS Tol PIS U E a B