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Cytochrome P450 3A4 Trilaciclib Trilaciclib Trilaciclib PIS1M1 Trilaciclib PIS1M1 Urinary Excretion and/or Bile duct Excretion Heme Hepatocytes Kidney Liver Cytosol Trilaciclib undergoes metabolism to give Trilaciclib PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Trilaciclib Trilaciclib Trilaciclib PIS1M1 Trilaciclib PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP3A4 Trila Trila Tri PIS Tri PIS U E a B Heme Hepatocytes Kidney Liver Cytosol Trilaciclib undergoes metabolism to give Trilaciclib PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Trila Trila Tri PIS Tri PIS U E a B