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Cytochrome P450 3A4 Vildagliptin Vildagliptin Vildagliptin PIS1M1 Vildagliptin PIS1M1 Urinary Excretion and/or Bile duct Excretion Heme Hepatocytes Kidney Liver Cytosol Vildagliptin undergoes metabolism to give Vildagliptin PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Vildagliptin Vildagliptin Vildagliptin PIS1M1 Vildagliptin PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP3A4 Equa Equa Vil PIS Vil PIS U E a B Heme Hepatocytes Kidney Liver Cytosol Vildagliptin undergoes metabolism to give Vildagliptin PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Equa Equa Vil PIS Vil PIS U E a B