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Cytochrome P450 3A4 Zaleplon Zaleplon Zaleplon PIS1M1 Zaleplon PIS1M1 Urinary Excretion and/or Bile duct Excretion Heme Hepatocytes Kidney Liver Cytosol Zaleplon undergoes metabolism to give Zaleplon PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Zaleplon Zaleplon Zaleplon PIS1M1 Zaleplon PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP3A4 Zaleplo Zaleplo Zal PIS Zal PIS U E a B Heme Hepatocytes Kidney Liver Cytosol Zaleplon undergoes metabolism to give Zaleplon PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Zaleplo Zaleplo Zal PIS Zal PIS U E a B