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Cytochrome P450 3A4 Zopiclone Zopiclone Zopiclone PIS1M1 Zopiclone PIS1M1 Urinary Excretion and/or Bile duct Excretion Heme Hepatocytes Kidney Liver Cytosol Zopiclone undergoes metabolism to give Zopiclone PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Zopiclone Zopiclone Zopiclone PIS1M1 Zopiclone PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP3A4 Zopiclo Zopiclo Zop PIS Zop PIS U E a B Heme Hepatocytes Kidney Liver Cytosol Zopiclone undergoes metabolism to give Zopiclone PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Zopiclo Zopiclo Zop PIS Zop PIS U E a B