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Cytochrome P450 1A2 Trifluridine Trifluridine Trifluridine PIS1M1 Trifluridine PIS1M1 Heme Urinary Excretion and/or Bile duct Excretion Hepatocytes Kidney Liver Cytosol Trifluridine undergoes metabolism to give Trifluridine PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP1A2 Trifluridine Trifluridine Trifluridine PIS1M1 Trifluridine PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP1A2 Viropti Viropti Tri PIS Tri PIS Heme U E a B Hepatocytes Kidney Liver Cytosol Trifluridine undergoes metabolism to give Trifluridine PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP1A2 Viropti Viropti Tri PIS Tri PIS U E a B