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Unknown Unknown Unknown Cytochrome P450 1A2 Cytochrome P450 1A2 Midodrine Midodrine Midodrine PIS1M1 Midodrine PIS1M2 Midodrine PIS1M1 Midodrine PIS1M2 Heme Heme Urinary Excretion and/or Bile duct Excretion Endoplasmic Reticulum Cytosol Hepatocyte Blood Vessel Liver kidney Bile Duct Blood Vessel Template2M undergoes metabolism to give Template2M PIS1M1 and Template2M PIS1M2.
Endoplasmic Reticulum Unknown Unknown Unknown CYP1A2 CYP1A2 Midodrine Midodrine Midodrine PIS1M1 Midodrine PIS1M2 Midodrine PIS1M1 Midodrine PIS1M2 Urinary Excretion and/or Bile duct Excretion