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Unknown Unknown Cytochrome P450 3A4 Cytochrome P450 3A4 Remdesivir PIS2M1 Remdesivir Remdesivir Remdesivir PIS1M1 Remdesivir PIS2M1 Heme Heme Urinary Excretion and/or Bile duct Excretion Endoplasmic Reticulum Cytosol Hepatocyte Endoplasmic Reticulum Liver Blood Vessel Kidney Bile Ducts Remdesivir undergoes metabolism to give Remdesivir PIS1M1 and Remdesivir PIS2M1.
Endoplasmic Reticulum Endoplasmic Reticulum Unknown Unknown CYP3A4 CYP3A4 Remdesivir PIS2M1 Remdesivir Remdesivir Remdesivir PIS1M1 Remdesivir PIS2M1 Urinary Excretion and/or Bile duct Excretion