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Unknown Unknown Cytochrome P450 3A4 Cytochrome P450 3A4 Tetracycline PIS2M1 Tetracycline Tetracycline Tetracycline PIS1M1 Tetracycline PIS2M1 Heme Heme Urinary Excretion and/or Bile duct Excretion Endoplasmic Reticulum Cytosol Hepatocyte Endoplasmic Reticulum Liver Blood Vessel Kidney Bile Ducts Tetracycline undergoes metabolism to give Tetracycline PIS1M1 and Tetracycline PIS2M1.
Endoplasmic Reticulum Endoplasmic Reticulum Unknown Unknown CYP3A4 CYP3A4 Tetracycline PIS2M1 Tetracycline Tetracycline Tetracycline PIS1M1 Tetracycline PIS2M1 Urinary Excretion and/or Bile duct Excretion