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Unknown Unknown Unknown Cytochrome P450 3A4 Cytochrome P450 3A4 Atogepant PIS1M1 Atogepant PIS1M2 Atogepant Atogepant Atogepant PIS1M1 Atogepant PIS1M2 Heme Heme Urinary Excretion and/or Bile duct Excretion Endoplasmic Reticulum Cytosol Hepatocyte Blood Vessel Liver kidney Bile Duct Blood Vessel Atogepant undergoes metabolism to give Atogepant PIS1M1 and Atogepant PIS1M2.
Endoplasmic Reticulum Unknown Unknown Unknown CYP3A4 CYP3A4 Atogepant PIS1M1 Atogepant PIS1M2 Atogepant Atogepant Atogepant PIS1M1 Atogepant PIS1M2 Urinary Excretion and/or Bile duct Excretion