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Unknown Unknown Unknown Cytochrome P450 3A4 Cytochrome P450 3A4 Mirtazapine PIS1M1 Mirtazapine PIS1M2 Mirtazapine Mirtazapine Mirtazapine PIS1M1 Mirtazapine PIS1M2 Heme Heme Urinary Excretion and/or Bile duct Excretion Endoplasmic Reticulum Cytosol Hepatocyte Blood Vessel Liver kidney Bile Duct Blood Vessel Mirtazapine undergoes metabolism to give Mirtazapine PIS1M1 and Mirtazapine PIS1M2.
Endoplasmic Reticulum Unknown Unknown Unknown CYP3A4 CYP3A4 Mirtazapine PIS1M1 Mirtazapine PIS1M2 Mirtazapine Mirtazapine Mirtazapine PIS1M1 Mirtazapine PIS1M2 Urinary Excretion and/or Bile duct Excretion